Identification of a <i>mepR</i> mutation associated with tigecycline resistance in a clinical <i>Staphylococcus aureus</i> isolate
This study provides the identification of a mepR variant contributing indirectly to tigecycline resistance via mediating increased expression of mepA in a clinical S. aureus isolate.
Authors
- Xiang‐Dang Du (ORCID: https://orcid.org/0000-0001-7431-7607)
- Štefan Schwarz (ORCID: https://orcid.org/0000-0002-6303-8212)
- Dexi Li
- Chenglong Li (ORCID: https://orcid.org/0000-0003-3043-7230)
- Hongjie Xing (ORCID: https://orcid.org/0000-0002-4902-392X)
- Likuan Zhang
Institutions
- Czech Academy of Sciences, Institute of Microbiology (CZ)
- Henan Agricultural University (CN)
- Freie Universität Berlin (DE)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2025-01-26
- DOI
- https://doi.org/10.1093/jac/dkaf034
- Primary Topic
- Antimicrobial Resistance in Staphylococcus
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China