STRUCTURAL DIFFERENCES IN CARDIAC ULTRASOUND BETWEEN H-TYPE AND NON-H-TYPE HYPERTENSION

H-type hypertension (HHT) is closely associated with cardiovascular and cerebrovascular complications, as well as peripheral vascular sclerosis. However, the mechanism underlying the relationship between HHT and cardiac remodeling is not completely clear. Therefore, this study aimed to investigate the structural differences in a cardiac ultrasound between patients with HHT and those with non-H-type hypertension (NHHT). This study was performed on 300 elderly patients ([Formula: see text] years) with essential hypertension and stratified into two groups based on their homocysteine (Hcy) levels: 150 with HHT and 150 with NHHT. The cardiac structure was assessed using color Doppler echocardiography. The key parameters were measured, including interventricular septal thickness (IVST), left ventricular posterior wall thickness (LVPWT), left ventricular mass index (LVMI), and others. The chi-square test was employed to examine the differences in cardiac ultrasound outcomes between HHT and NHHT groups. Left ventricular hypertrophy (LVH) was observed in 118 patients (78.7%) in the HHT group and 75 patients (50.0%) in the NHHT group. The HHT group demonstrated a significantly higher prevalence of LVH ([Formula: see text], [Formula: see text]). Patients with HHT had significantly higher systolic blood pressure, Hcy levels, LVPWT, IVST, and LVMI compared with those with NHHT: systolic blood pressure ([Formula: see text] [Formula: see text]mm Hg versus [Formula: see text] [Formula: see text]mm Hg), Hcy ([Formula: see text]mol/L versus [Formula: see text] [Formula: see text] [Formula: see text]mol/L), LVPWT ([Formula: see text] [Formula: see text]mm versus [Formula: see text] [Formula: see text]mm), IVST ([Formula: see text] [Formula: see text]mm versus [Formula: see text] [Formula: see text]mm), and LVMI ([Formula: see text] [Formula: see text]g/m 2 versus [Formula: see text] [Formula: see text]g/m 2 ). The correlation analysis showed a notable positive relationship between Hcy levels and LVMI ([Formula: see text], [Formula: see text]), and between systolic blood pressure and LVMI ([Formula: see text], [Formula: see text]). The occurrence of LVH was notably greater in patients with HHT than in those with NHHT. Furthermore, Hcy and systolic blood pressure levels were positively correlated with LVMI.