Massive edema of ovary masquerading as neoplasm in a preteen girl

Massive ovarian oedema, though rare, frequently mimics an ovarian neoplasm, both clinically and radiologically. Here, we discuss the case of a 12-year-old girl who presented with intermittent pain in the lower abdomen for last one month associated with vomiting. A suspicion of germ cell neoplasm was raised on ultrasound despite mildly raised serum markers. Microscopy from left salpingo-ophrectomy specimen revealed marked oedema of ovarian stroma with preserved primordial follicles at the periphery only. This case highlights the importance of a high index of suspicion, clinically, radiologically and pathologically, especially in cases with only mildly raised serum markers to avoid unwarranted surgery and preserve hormonal function as well as fertility in some cases.

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Publication Details

Journal
Indian Journal of Pathology and Microbiology
Published
2025-02-07
DOI
https://doi.org/10.4103/ijpm.ijpm_83_24
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
Field-Weighted Citation Impact
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article

Massive edema of ovary masquerading as neoplasm in a preteen girl

Sandeep Mathur, Ruchi Rathore, Surabhi Jain, Rajesh Kumari
Indian Journal of Pathology and Microbiology
Ovarian cancer diagnosis and treatment
article

Massive edema of ovary masquerading as neoplasm in a preteen girl

Sandeep Mathur, Ruchi Rathore, Surabhi Jain, Rajesh Kumari
article en

Abstract

Massive ovarian oedema, though rare, frequently mimics an ovarian neoplasm, both clinically and radiologically. Here, we discuss the case of a 12-year-old girl who presented with intermittent pain in the lower abdomen for last one month associated with vomiting. A suspicion of germ cell neoplasm was raised on ultrasound despite mildly raised serum markers. Microscopy from left salpingo-ophrectomy specimen revealed marked oedema of ovarian stroma with preserved primordial follicles at the periphery only. This case highlights the importance of a high index of suspicion, clinically, radiologically and pathologically, especially in cases with only mildly raised serum markers to avoid unwarranted surgery and preserve hormonal function as well as fertility in some cases.

Indian Journal of Pathology and MicrobiologyVol. 68(2)
All India Institute of Medical Sciences (IN)
Good health and well-being
Openalex Percentile: Top 97%
Ovarian cancer diagnosis and treatment
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Massive edema of ovary masquerading as neoplasm in a preteen girl — Sandeep Mathur, Ruchi Rathore, et al. · Indian Journal of Pathology and Microbiology (2025) | TGRS Research Map | TGRS