Synthesis, Photophysics, and Potential Antifungal Activity of Benzo[a]phenoxazines

The synthesis and full characterization of new hydroxyl benzo[a]phenoxazinium chlorides with N-(di)propyl and/or N-isopropyl groups in the 5 and 9 positions are described.Photophysical studies carried out in ethanol and water revealed strong absorbances and significant fluorescence emissions at up to 676 nm.The antifungal activity was assessed against Saccharomyces cerevisiae and the results provide possible directions for further studies.

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Published
2024-11-14
DOI
https://doi.org/10.3390/ecsoc-28-20172
Primary Topic
Phenothiazines and Benzothiazines Synthesis and Activities
Type
article
Field-Weighted Citation Impact
0.00

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article

Synthesis, Photophysics, and Potential Antifungal Activity of Benzo[a]phenoxazines

M. Sameiro T. Gonçalves, Bárbara O. Guimarães, Maria João Sousa
Phenothiazines and Benzothiazines Synthesis and Activities
article

Synthesis, Photophysics, and Potential Antifungal Activity of Benzo[a]phenoxazines

M. Sameiro T. Gonçalves, Bárbara O. Guimarães, Maria João Sousa
article en

Abstract

The synthesis and full characterization of new hydroxyl benzo[a]phenoxazinium chlorides with N-(di)propyl and/or N-isopropyl groups in the 5 and 9 positions are described.Photophysical studies carried out in ethanol and water revealed strong absorbances and significant fluorescence emissions at up to 676 nm.The antifungal activity was assessed against Saccharomyces cerevisiae and the results provide possible directions for further studies.

University of Minho (PT)
China Building Materials Academy, Fundação para a Ciência e a Tecnologia
Zero hunger
Openalex Percentile: Top 78%
Phenothiazines and Benzothiazines Synthesis and Activities
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