Total flavonoids isolated from Eucommia ulmoides can alleviate bone loss and regulate intestinal microbiota in ovariectomized rats
TFEL can prevent osteoporosis in OVX rats and has no toxic side effects. Meanwhile, TFEL can increase the diversity and improve the composition of intestinal flora in OVX rats.
Authors
- Bin Yin (ORCID: https://orcid.org/0000-0003-2479-7301)
- Tiejun Li (ORCID: https://orcid.org/0000-0002-4147-446X)
- Yuankun Zhai (ORCID: https://orcid.org/0000-0001-8156-1368)
- Ningli Li (ORCID: https://orcid.org/0000-0001-6734-229X)
- Qin Li (ORCID: https://orcid.org/0000-0001-5015-0750)
- Yun Zhang (ORCID: https://orcid.org/0000-0003-1614-1943)
- Bowen Wang (ORCID: https://orcid.org/0000-0003-0297-9008)
- Cory J. Xian (ORCID: https://orcid.org/0000-0002-8467-2845)
- Yingying Li (ORCID: https://orcid.org/0000-0003-3243-1975)
- Mingzhen Yang (ORCID: https://orcid.org/0000-0002-9667-1583)
Institutions
- University of South Australia (AU)
- Henan University (CN)
- Peking University (CN)
- Kaifeng University (CN)
- First Affiliated Hospital of Henan University (CN)
- Luoyang Orthopedic-Traumatological Hospital of Henan Province (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-02-07
- DOI
- https://doi.org/10.3389/fphar.2025.1513863
- Citations
- 2
- Primary Topic
- Bone Metabolism and Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- Shanxi University
- Henan University
- National Key Research and Development Program of China