Improved real-world UHPLC-MS/MS iohexol analysis; thawed samples, improved calibration curve, and additional matrices
Human EDTA plasma samples can be stored up to 9 weeks at room temperature, 4°C, 37°C, and 37°C with 55°C daily temperature spikes. The samples can be analyzed using a two-point calibration curve and are partial validated for serum-, heparin plasma-, urine-, EDTA whole blood-, and lithium whole blood iohexol samples.
Authors
- Daan J. Touw (ORCID: https://orcid.org/0000-0002-1429-4789)
- Lenneke A. T. Junier
- Jasper Stevens (ORCID: https://orcid.org/0000-0003-1601-9008)
- A. Mireille A. Wessels
Institutions
- University Medical Center Groningen (NL)
- University of Groningen (NL)
Publication Details
- Journal
- Bioanalysis
- Published
- 2025-02-07
- DOI
- https://doi.org/10.1080/17576180.2025.2462429
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- HORIZON EUROPE Framework Programme