Exploring RNA cargo in extracellular vesicles for pleural mesothelioma detection
This is the first study to characterize the transcriptomic profile of EVs secreted by PM primary cell cultures, demonstrating their potential as biomarker source for early detection. Further investigation of the functional role of PM-EVs will provide new insights into disease biology and therapeutic avenues.
Authors
- Agnieszka Kraft (ORCID: https://orcid.org/0000-0001-7672-2032)
- Michaela B. Kirschner (ORCID: https://orcid.org/0000-0001-7444-9829)
- Valentina Boeva (ORCID: https://orcid.org/0000-0002-4382-7185)
- V. Orlowski
- Mayura Meerang (ORCID: https://orcid.org/0000-0002-5546-3120)
- Manuel Ronner
- Isabelle Opitz (ORCID: https://orcid.org/0000-0001-5900-9040)
- Caroline Bodmer
Institutions
- Délégation Paris 5 (FR)
- SIB Swiss Institute of Bioinformatics (CH)
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- University of Zurich (CH)
- Université Paris Cité (FR)
- ETH Zurich (CH)
- University Hospital of Zurich (CH)
- Institut Cochin (FR)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-02-07
- DOI
- https://doi.org/10.1186/s12885-025-13617-y
- Citations
- 1
- Primary Topic
- Occupational and environmental lung diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- National Science Foundation
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Fudan University
- Universitätsspital Zürich