Preconception Paternal Alcohol Consumption Elicits Postnatal Changes in Neural Retinas of the Offspring
This study provides pioneering evidence that PPAC contributes to FASD-related ocular defects including negative impacts on retinal light responses and retinal thinning in young adult offspring. Thus the adverse impact of paternal alcohol consumption prior to conception on their offspring (from childhood to early adulthood) should be considered as seriously as the maternal contribution to FASD.
Authors
- Kelsey Cox
- Michael L. Ko (ORCID: https://orcid.org/0000-0002-2723-2464)
- Kara N. Thomas (ORCID: https://orcid.org/0000-0001-5311-6574)
- Michael C. Golding (ORCID: https://orcid.org/0000-0003-1631-2175)
- Dylan L. Pham (ORCID: https://orcid.org/0000-0002-3470-4618)
- Weilin Chen (ORCID: https://orcid.org/0009-0005-8131-0135)
- Gladys Yi-Ping Ko
- Kofi Owusu-Ansah
Institutions
- National Chung Hsing University (TW)
- Physical Sciences (United States) (US)
- Blinn College (US)
- Texas A&M University (US)
- Bryan College (US)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-02-06
- DOI
- https://doi.org/10.1167/iovs.66.2.16
- Primary Topic
- Prenatal Substance Exposure Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health