Nijmegen Breakage Syndrome Complicated by Colon Cancer with Liver Metastasis: A Case Report

Background Nijmegen Breakage Syndrome (NBS) is a rare autosomal recessive DNA repair disorder that increases the risk of malignant tumors. Colorectal cancer is one of the common malignant tumors, and its liver metastasis is a focal point and challenge in the treatment of colorectal cancer. Case presentation A 24-year-old male was diagnosed with Nijmegen Breakage Syndrome Complicated by Colon Cancer with Liver Metastasis: A Case Report Conclusions Early identification of Nijmegen Breakage Syndrome (NBS) is crucial for making correct diagnoses, conducting genetic counseling, and for cancer screening, risk reduction, and selection of anticancer treatments.