Amidophosphine Boranes as Easy Reducing Agents for Efficient Conversion of Nitro Compounds to Primary Amines With Iron Catalyst

ABSTRACT We report a direct and efficient methodology for the hydroboration of aliphatic and aryl nitro compounds using amidophosphine‐borane {(C 6 H 5 )CH 2 N(PPh) 2 (BH 3 ) 2 } in the presence of iron(II) chloride as a catalyst under mild conditions to form primary amines after hydrolysis. Solid amidophosphine‐boranes are user‐friendly and readily synthesized, revealing remarkable reducing properties toward a comprehensive range of nitro compounds. The scalability of the present approach is defined by performing gram‐scale reactions and synthesis of different pharmaceuticals like paracetamol and benzocaine, demonstrating the synthetic applicability of the current strategy.