Is it fungal? No, it is not. A case of Pythium <em>keratitis</em> from Sri Lanka

Infectious agents are the commonest cause of corneal ulcers. Pythium insidiosum is a fungus-like aquatic oomycete capable of rarely causing human infections. Keratitis caused by Pythium insidiosum is associated with high ocular morbidity.A 13-year-old boy from rural Sri Lanka presented with pain and tearing in the left eye for several days. While there was no history of trauma, he had bathed in a lake. A central corneal ulcer with satellite lesions was found on examination. The ulcer was non-responsive to topical and systemic antimicrobial therapy, and he underwent penetrating keratoplasty. However, the infection recurred and a second penetrating keratoplasty was performed a week later. Fungal studies indicated that both his corneal buttons were positive for Pythium species. Continued aggressive antimicrobial therapy resulted in a quiet, vascularised eye with retained perception of light vision.Pythium keratitis requires prompt and adequate surgical and medical treatment. Clinicians’ awareness is important to diagnose this entity early.

Authors

Publication Details

Journal
Sri Lankan Journal of Infectious Diseases
Published
2025-02-06
DOI
https://doi.org/10.4038/sljid.v15i1.8677
Primary Topic
Infectious Diseases and Mycology
Type
article
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article

Is it fungal? No, it is not. A case of Pythium keratitis from Sri Lanka

P. G. R. I. S. Welagedara, P. I. Jayasekera, S. C. De Silva, K. R. Dayawansa et al.
1 links
Sri Lankan Journal of Infectious Diseases
Infectious Diseases and Mycology
article

Is it fungal? No, it is not. A case of Pythium keratitis from Sri Lanka

P. G. R. I. S. Welagedara, P. I. Jayasekera, S. C. De Silva, K. R. Dayawansa, L. S. M. Sigera
article en

Abstract

Infectious agents are the commonest cause of corneal ulcers. Pythium insidiosum is a fungus-like aquatic oomycete capable of rarely causing human infections. Keratitis caused by Pythium insidiosum is associated with high ocular morbidity.A 13-year-old boy from rural Sri Lanka presented with pain and tearing in the left eye for several days. While there was no history of trauma, he had bathed in a lake. A central corneal ulcer with satellite lesions was found on examination. The ulcer was non-responsive to topical and systemic antimicrobial therapy, and he underwent penetrating keratoplasty. However, the infection recurred and a second penetrating keratoplasty was performed a week later. Fungal studies indicated that both his corneal buttons were positive for Pythium species. Continued aggressive antimicrobial therapy resulted in a quiet, vascularised eye with retained perception of light vision.Pythium keratitis requires prompt and adequate surgical and medical treatment. Clinicians’ awareness is important to diagnose this entity early.

Sri Lankan Journal of Infectious DiseasesVol. 15(1)
Openalex Percentile: Top 98%
Infectious Diseases and Mycology
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Is it fungal? No, it is not. A case of Pythium <em>keratitis</em> from Sri Lanka — P. G. R. I. S. Welagedara, P. I. Jayasekera, et al. · Sri Lankan Journal of Infectious Diseases (2025) | TGRS Research Map | TGRS