Comparison of intensity normalization methods in prostate, brain, and breast cancer multi-parametric magnetic resonance imaging
Our results suggest that intensity normalization using the Z-score of intensity within prostate, breast, and brain MR images produces the most comparable intensities between sites, MR vendors, magnetic field strength, and prostate endorectal coil usage. Likewise, Z-score normalization provided the highest percentage of radiomic features that were statistically equal across the three organs.
Authors
- Fitzgerald Kyereme
- Biprojit Nath
- Aleksandra Winiarz (ORCID: https://orcid.org/0000-0002-6994-5796)
- Peter S. LaViolette (ORCID: https://orcid.org/0000-0002-9602-6891)
- Stephanie Vincent-Sheldon
- Samuel Bobholz (ORCID: https://orcid.org/0000-0003-1525-7418)
- Savannah Duenweg (ORCID: https://orcid.org/0000-0003-4010-7737)
- Allison K. Lowman (ORCID: https://orcid.org/0000-0002-2520-8145)
- Michael Barrett (ORCID: https://orcid.org/0000-0003-1775-8347)
Institutions
- Medical College of Wisconsin (US)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-02-07
- DOI
- https://doi.org/10.3389/fonc.2025.1433444
- Citations
- 3
- Primary Topic
- Radiomics and Machine Learning in Medical Imaging
- Type
- article
- Field-Weighted Citation Impact
- 4.08
Funders
- National Cancer Institute