Utilizing bioinformatics and machine learning to identify CXCR4 gene-related therapeutic targets in diabetic foot ulcers
The findings suggest that CXCR4 and its related pathways play an important role in the pathogenesis of DFUs, providing a new perspective on targeted therapy for wound healing in diabetic patients. Further validation of the role of CXCR4 is expected to establish it as an important target in DFU management.
Authors
- Hengyan Zhang (ORCID: https://orcid.org/0000-0001-6549-0002)
- Yangwen Liu
- Ye Zhou (ORCID: https://orcid.org/0000-0003-0912-9241)
- Licong Yang (ORCID: https://orcid.org/0000-0002-6570-8056)
- Heguo Yan
- Changxing Huang
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-02-07
- DOI
- https://doi.org/10.3389/fendo.2025.1520845
- Citations
- 2
- Primary Topic
- Diabetic Foot Ulcer Assessment and Management
- Type
- article
- Field-Weighted Citation Impact
- 2.59