Rheumatoid arthritis associated cytokines and therapeutics modulate immune checkpoint receptor expression on T cells

This study points to an important and intricate relationship between cytokines and IRs in shaping immune responses in autoimmune pathology. The modulation of IR expression by RA-associated cytokines and SOC therapeutics provides new insights for the use of targeted treatments in managing RA pathology.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-02-06
DOI
https://doi.org/10.3389/fimmu.2025.1534462
Citations
3
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
3.14
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article

Rheumatoid arthritis associated cytokines and therapeutics modulate immune checkpoint receptor expression on T cells

Dana A. Emerson, Pia P. Yachi, Eve Merriman
3 citations
Frontiers in Immunology
Cancer Immunotherapy and Biomarkers
3.14
article

Rheumatoid arthritis associated cytokines and therapeutics modulate immune checkpoint receptor expression on T cells

Dana A. Emerson, Pia P. Yachi, Eve Merriman
article en
3 citations

Abstract

This study points to an important and intricate relationship between cytokines and IRs in shaping immune responses in autoimmune pathology. The modulation of IR expression by RA-associated cytokines and SOC therapeutics provides new insights for the use of targeted treatments in managing RA pathology.

Frontiers in ImmunologyVol. 16
Eli Lilly (United States) (US)
Openalex Percentile: Top 9%
Cancer Immunotherapy and Biomarkers
3.14
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Rheumatoid arthritis associated cytokines and therapeutics modulate immune checkpoint receptor expression on T cells — Dana A. Emerson, Pia P. Yachi, et al. · Frontiers in Immunology (2025) | TGRS Research Map | TGRS