Quzhou Aurantii Fructus Flavonoids Ameliorate Inflammatory Responses, Intestinal Barrier Dysfunction in DSS-Induced Colitis by Modulating PI3K/AKT Signaling Pathway and Gut Microbiome
QAFF could ameliorate inflammatory responses and intestinal barrier dysfunction in DSS-induced UC mice probably by modulating the PI3K/AKT signaling pathway and gut microbiome, offering promising evidence for the therapeutic potential of QAFF in UC treatment.
Authors
- Jianhua Qi (ORCID: https://orcid.org/0000-0002-2723-1648)
- Jiahui Chen (ORCID: https://orcid.org/0009-0004-3037-027X)
- Haiou Wang (ORCID: https://orcid.org/0000-0003-1755-2648)
- Meizi Tian (ORCID: https://orcid.org/0000-0003-1557-8932)
- Yiping Ye (ORCID: https://orcid.org/0000-0002-1383-4296)
- Lijuan Gao (ORCID: https://orcid.org/0000-0002-4069-3337)
- Wenkang Huang
- Qin Li (ORCID: https://orcid.org/0000-0002-9797-2636)
- Xiaotong Liu (ORCID: https://orcid.org/0000-0002-3618-0168)
- Xiaoya Pan
Institutions
- Hangzhou Medical College (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/jir.s500014
- Citations
- 6
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 4.84