Detection of chimeric alpha-defensin transcripts and peptides in mouse Paneth cells
We show the existence of chimeric <i>Defa</i> transcripts and peptides in mice that are biologically active. We propose a possible stochatic mechanism or that the activation of the UPR patway may play a role in their production.
Authors
- Steven Timmermans (ORCID: https://orcid.org/0000-0002-5152-9620)
- Charlotte Wallaeys (ORCID: https://orcid.org/0000-0001-6838-3595)
- Claude Libert (ORCID: https://orcid.org/0000-0001-6408-036X)
- Somara De Beul
- Natalia Garcia-Gonzales
Institutions
- Vlaams Instituut voor Biotechnologie (BE)
- Ghent University (BE)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-02-06
- DOI
- https://doi.org/10.3389/fimmu.2025.1543059
- Citations
- 1
- Primary Topic
- Antimicrobial Peptides and Activities
- Type
- article
- Field-Weighted Citation Impact
- 1.18
Funders
- Fonds Wetenschappelijk Onderzoek
- Universiteit Gent
- Vlaamse regering