Potent P2Y12 inhibitors in patients with acute myocardial infarction and cardiogenic shock

In patients with AMI complicated by cardiogenic shock, the use of potent P2Y<sub>12</sub> inhibitors was associated with a lower risk of MACE compared with clopidogrel, without an increased risk of BARC type 2 or greater bleeding. The current data supports the use of potent P2Y<sub>12</sub> inhibitors in patients with AMI and cardiogenic shock, except in patients aged ≥ 75 years or receiving VA-ECMO support.

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Publication Details

Journal
Critical Care
Published
2025-02-06
DOI
https://doi.org/10.1186/s13054-025-05277-y
Primary Topic
Antiplatelet Therapy and Cardiovascular Diseases
Type
article
Field-Weighted Citation Impact
0.00

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article

Potent P2Y12 inhibitors in patients with acute myocardial infarction and cardiogenic shock

Joo Myung Lee, Ki Hong Choi, Seung‐Hyuk Choi, Kyeong Ho Yun et al.
Critical Care
Antiplatelet Therapy and Cardiovascular Diseases
article

Potent P2Y12 inhibitors in patients with acute myocardial infarction and cardiogenic shock

Joo Myung Lee, Ki Hong Choi, Seung‐Hyuk Choi, Kyeong Ho Yun, Woochan Kwon, Kiyuk Chang, Joo-Yong Hahn, Yisik Kim, Jeong Hoon Yang, Jinhwan Jo, Hyun Kuk Kim, Young Joon Hong, Seung‐Ho Hur, Hyo‐Soo Kim, Junho Ha, Young Bin Song, Ju Han Kim, Yong Hwan Park, Myung‐Ho Jeong, Chang‐Hwan Yoon, Jin‐Yong Hwang, Hyeon‐Cheol Gwon, Taek Kyu Park, Jin‐Ok Jeong, Doosup Shin, Hyun Sung Joh, Jang‐Whan Bae, Hun Sik Park, Seung Hun Lee, Chang‐Hoon Kim, Young Keun Ahn, Doo‐Il Kim
article en

Abstract

In patients with AMI complicated by cardiogenic shock, the use of potent P2Y<sub>12</sub> inhibitors was associated with a lower risk of MACE compared with clopidogrel, without an increased risk of BARC type 2 or greater bleeding. The current data supports the use of potent P2Y<sub>12</sub> inhibitors in patients with AMI and cardiogenic shock, except in patients aged ≥ 75 years or receiving VA-ECMO support.

Critical CareVol. 29(1)
Seoul National University (KR), Chungbuk National University (KR), Samsung (South Korea) (KR), Kyungpook National University Hospital (KR), Samsung Medical Center (KR), Seoul National University Hospital (KR), Seoul National University Bundang Hospital (KR), Gyeongsang National University Hospital (KR), Chonnam National University Hospital (KR), St. Francis Hospital (US), SNUH SMG-SNU Boramae Medical Center (KR), Chosun University Hospital (KR), Inje University Haeundae Paik Hospital (KR), Kangbuk Samsung Hospital (KR), Keimyung University Dongsan Medical Center (KR), Jeonbuk National University Hospital (KR), Chungnam National University Hospital (KR), The Catholic University of Korea Seoul St. Mary's Hospital (KR), Keimyung University (KR), Wonkwang University (KR), Sungkyunkwan University (KR), Catholic University of Korea (KR)
Centers for Disease Control and Prevention, Korea Centers for Disease Control and Prevention
Good health and well-being
Openalex Percentile: Top 96%
Antiplatelet Therapy and Cardiovascular Diseases
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