Genetic and Plasma Proteomic Approaches to Identify Therapeutic Targets for Graves’ Disease and Graves’ Ophthalmopathy
By synthesizing proteomic and genetic data, we identified several protein biomarkers for GD, with one linked to both GD and GO and two other protein biomarkers specific to GO onset, which provides valuable insights into the etiology and potential therapeutic targets for the two diseases.
Authors
- Jiang Li (ORCID: https://orcid.org/0009-0005-6253-618X)
- Yuefeng Yu (ORCID: https://orcid.org/0000-0001-7439-4231)
- Yuying Wang (ORCID: https://orcid.org/0000-0002-6761-1936)
- Yuetian Yu (ORCID: https://orcid.org/0000-0002-0193-4046)
- Ningjian Wang (ORCID: https://orcid.org/0000-0001-9591-6991)
- Yingli Lu (ORCID: https://orcid.org/0000-0002-5117-1614)
- Bin Wang (ORCID: https://orcid.org/0000-0002-2662-1986)
- Ying Sun (ORCID: https://orcid.org/0000-0002-3104-4394)
- Chao Ke (ORCID: https://orcid.org/0000-0003-1918-9600)
- Yi Chen (ORCID: https://orcid.org/0000-0002-2324-9402)
- Mengjun Tang (ORCID: https://orcid.org/0000-0002-9088-7682)
Institutions
- Wenzhou Medical University (CN)
- Shanghai Ninth People's Hospital (CN)
- Zhejiang Taizhou Hospital (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- ImmunoTargets and Therapy
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/itt.s494692
- Citations
- 4
- Primary Topic
- Ophthalmology and Eye Disorders
- Type
- article
- Field-Weighted Citation Impact
- 5.89
Funders
- National Natural Science Foundation of China