Oleanolic Acid Slows Down Aging Through IGF-1 Affecting the PI3K/AKT/mTOR Signaling Pathway
The findings suggested that OA slowed down aging by inhibiting the PI3K/AKT/mTOR expression through IGF-1. These findings suggest OA as a potential new drug and its mechanisms for anti-aging.
Authors
- Didi Wang (ORCID: https://orcid.org/0000-0002-0813-755X)
- Pengxia Zhang (ORCID: https://orcid.org/0000-0002-6114-1080)
- Yan Xu (ORCID: https://orcid.org/0009-0008-4491-4804)
- Wang Wang (ORCID: https://orcid.org/0000-0001-9093-412X)
- Tao Zhang (ORCID: https://orcid.org/0009-0008-5991-0101)
- Jun Wei (ORCID: https://orcid.org/0000-0001-8888-0417)
- Zebin Mao
Institutions
- Jiamusi University (CN)
- Peking University (CN)
Publication Details
- Journal
- Molecules
- Published
- 2025-02-06
- DOI
- https://doi.org/10.3390/molecules30030740
- Citations
- 8
- Primary Topic
- Natural product bioactivities and synthesis
- Type
- article
- Field-Weighted Citation Impact
- 6.45