Causal Effect Between Gut Microbiota, Gut Bacterial Pathway, and Chronic Spontaneous Urticaria: A Large-Scale Bidirectional Mendelian Randomization Analysis
Our study confirmed a causal association between gut microbiota and CSU, with the the metabolic pathway being a potential mediator. Our findings provide new insights for further mechanistic and clinical studies in CSU.
Authors
- Hongliang Cao (ORCID: https://orcid.org/0000-0002-9342-7980)
- Qingqing Jiao (ORCID: https://orcid.org/0000-0001-6278-2608)
- Jia Chen (ORCID: https://orcid.org/0000-0001-6597-8577)
- Hui Shen (ORCID: https://orcid.org/0000-0003-3408-8154)
- Zijun Lu (ORCID: https://orcid.org/0000-0003-2959-7712)
- Jian Ji (ORCID: https://orcid.org/0000-0003-1175-7730)
- Yimin Yao (ORCID: https://orcid.org/0000-0003-2134-549X)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Soochow University (CN)
- Second Affiliated Hospital of Soochow University (CN)
- Hanzhong People's Hospital (CN)
- First Affiliated Hospital of Soochow University (CN)
- The Fifth People’s Hospital of Suzhou (CN)
Publication Details
- Journal
- Journal of Investigational Allergology and Clinical Immunology
- Published
- 2025-02-06
- DOI
- https://doi.org/10.18176/jiaci.1054
- Citations
- 2
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 1.61