A Physiological Analysis of Prasara Avastha in the Context of Shadkriyakala: An Ayurvedic Perspective

Background: Shadkriyakala, an important concept in Ayurveda, represents the six stages of disease progression. Acharya Sushruta detailed this framework in the 21st chapter of Sutrasthana, emphasizing the 'right time' for therapeutic intervention to prevent and treat disease. Objective- To explore the physiological implications of Prasara Avastha, one of the stages of Shadkriyakala, by integrating Ayurvedic principles with contemporary biomedical perspectives, aiming to enhance understanding of its role in disease progression and prevention. Methods: A literature review of classical Ayurvedic texts, including Sushruta Samhita, and modern biomedical research was conducted to analyse the concept of Prasara Avastha. Correlations between dosha movement and pathophysiological changes were examined to identify preventive strategies. Results: Prasara Avastha marks the phase where doshas (biological humors) spread from their original sites, increasing the potential for disease manifestation. Understanding this stage enables early intervention, reducing the risk of disease progression and complications. Conclusion: Comprehension and application of Shadkriyakala, particularly Prasara Avastha, can significantly improve disease management and prevention. Early recognition of dosha movement allows for timely therapeutic measures, aligning with both Ayurvedic and modern medical approaches. Key words: Ayurveda, Dosha, Shadkriyakala, Prasara Avastha