Topological Distribution of <i>KCNH2</i> Variants and Genotype‐Phenotype Relationship in Patients With Long QT Syndrome
KCNH2 nsSNVs located at the N-terminal, S5-H5-S6 region, and the PAS and SF functional domains are associated with an increased risk of life-threatening cardiac events in LQT2 patients.
Authors
- Zhenhong Jiang (ORCID: https://orcid.org/0000-0002-8807-0681)
- Yang Shen (ORCID: https://orcid.org/0000-0003-3470-4324)
- Ying Shao
- Yuhao Su
- Kui Hong (ORCID: https://orcid.org/0000-0001-9416-0862)
- Ramón Brugada
- Daowu Wang
- Hongyu Liu (ORCID: https://orcid.org/0000-0003-0359-1283)
Institutions
- Nanchang University (CN)
- Second Affiliated Hospital of Nanchang University (CN)
- Institut d'Investigació Biomèdica de Girona (ES)
- Jiangsu Province Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Pacing and Clinical Electrophysiology
- Published
- 2025-02-06
- DOI
- https://doi.org/10.1111/pace.15145
- Citations
- 1
- Primary Topic
- Cardiac electrophysiology and arrhythmias
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China