Aggregated α-synuclein in erythrocytes as a potential biomarker for idiopathic Parkinson's Disease
The elevation of aggregated α-synuclein in GU-PD erythrocytes, which is not related to aging, suggests that these forms may be indicative of PD pathology and possibly accumulate upon disease establishment. As such, aggregated α-synuclein in RBCs could be a potential biomarker for PD diagnosis.
Authors
- Nikolaos Papagiannakis (ORCID: https://orcid.org/0000-0002-8401-8472)
- Evangelia Emmanouilidou (ORCID: https://orcid.org/0000-0003-3106-8270)
- Leonidas Stefanis (ORCID: https://orcid.org/0000-0003-3569-8990)
- Matina Maniati
- Konstantina Dimoula
Institutions
- National and Kapodistrian University of Athens (GR)
- Academy of Athens (GR)
- Biomedical Research Foundation of the Academy of Athens (GR)
- Eginition Hospital (GR)
Publication Details
- Journal
- Parkinsonism & Related Disorders
- Published
- 2025-02-06
- DOI
- https://doi.org/10.1016/j.parkreldis.2025.107321
- Citations
- 5
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 6.95
Funders
- European Commission
- General Secretariat for Research and Technology
- National and Kapodistrian University of Athens
- Hellenic Foundation for Research and Innovation