Facile Conversion of Ketene Dithioacetals to Imidazolidines, Oxazolidines, and Thiazolidines in a Deep Eutectic Solvent
An efficient green synthesis of structurally diverse azole heterocycles by treating ketene diethyl dithioacetals with various binucleophiles has been achieved. Deep eutectic solvent (DES) has been used as a reaction medium, and the optimized conditions and recyclability of the DES have been investigated. The title heterocyclic compounds, namely imidazolidines, 1,3-oxazolidines, and 1,3-thiazolidines, could be generated from easily accessible ketene dithioacetals by reacting with ethylene diamine, ethanolamine, and cysteamine, respectively.
Authors
- Rajeev Kumar Singh (ORCID: https://orcid.org/0000-0002-0136-9243)
- N. S. Singh (ORCID: https://orcid.org/0000-0003-2883-6726)
- Okram Mukherjee Singh (ORCID: https://orcid.org/0000-0001-9406-2015)
- Langpoklakpam Gellina Chanu
- Lokendra Singh (ORCID: https://orcid.org/0000-0002-9970-1258)
Institutions
- Manipur University (IN)
Publication Details
- Journal
- Russian Journal of Organic Chemistry
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1134/s107042802410248
- Primary Topic
- Synthesis of heterocyclic compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00