Synthesis and Oxidative Transformations of 5,7-Bis(4-methoxyphenyl)-1,2,3,4,4a,5-hexahydro-13H-benzimidazo[2,1-j]quinoline

The reaction of 4,4′-dimethoxychalcone with cyclohexanone gave 1,5-diketone which was con­densed with o-phenylenediamine to produce 5,7-bis(4-methoxyphenyl)-1,2,3,4,4a,5-hexahydro-13H-benzimid­azo[2,1-j]quinoline. The oxidation and oxidative coupling of the latter with some primary amines and benzoylacetonitrile afforded fused heterocyclic p-quinoid compounds.

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Publication Details

Journal
Russian Journal of Organic Chemistry
Published
2024-12-01
DOI
https://doi.org/10.1134/s1070428024120078
Primary Topic
Synthesis and biological activity
Type
article
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article

Synthesis and Oxidative Transformations of 5,7-Bis(4-methoxyphenyl)-1,2,3,4,4a,5-hexahydro-13H-benzimidazo[2,1-j]quinoline

K. V. Maslov, O. Yu. Slabko, L. N. Harchenko
Russian Journal of Organic Chemistry
Synthesis and biological activity
article

Synthesis and Oxidative Transformations of 5,7-Bis(4-methoxyphenyl)-1,2,3,4,4a,5-hexahydro-13H-benzimidazo[2,1-j]quinoline

K. V. Maslov, O. Yu. Slabko, L. N. Harchenko
article en

Abstract

The reaction of 4,4′-dimethoxychalcone with cyclohexanone gave 1,5-diketone which was con­densed with o-phenylenediamine to produce 5,7-bis(4-methoxyphenyl)-1,2,3,4,4a,5-hexahydro-13H-benzimid­azo[2,1-j]quinoline. The oxidation and oxidative coupling of the latter with some primary amines and benzoylacetonitrile afforded fused heterocyclic p-quinoid compounds.

Russian Journal of Organic ChemistryVol. 60(12)
Far Eastern Federal University (RU)
Openalex Percentile: Top 81%
Synthesis and biological activity
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