Reaction of Substituted Chalcone with Guanidine in the Presence of Hydrogen Peroxide

A new compound, 2-amino-5-(4-bromophenyl)-5-{5-bromo-2-[(prop-2-en-1-yl)oxy]benzyl}-3,5-dihydro-4H-imidazol-4-one, has been synthesized by the reaction of (2E)-1-(4-bromophenyl)-3-{5-bromo-2-[(prop-2-en-1-yl)oxy]benzyl}prop-2-en-1-one with guanidine in the presence of hydrogen peroxide. The product structure was determined by NMR spectroscopy and X-ray analysis. A probable reaction mechanism has been proposed.

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Publication Details

Journal
Russian Journal of Organic Chemistry
Published
2024-12-01
DOI
https://doi.org/10.1134/s107042802412025x
Primary Topic
Synthesis and biological activity
Type
article
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article

Reaction of Substituted Chalcone with Guanidine in the Presence of Hydrogen Peroxide

Victor N. Khrustalev, I. G. Mamedov
Russian Journal of Organic Chemistry
Synthesis and biological activity
article

Reaction of Substituted Chalcone with Guanidine in the Presence of Hydrogen Peroxide

Victor N. Khrustalev, I. G. Mamedov
article en

Abstract

A new compound, 2-amino-5-(4-bromophenyl)-5-{5-bromo-2-[(prop-2-en-1-yl)oxy]benzyl}-3,5-dihydro-4H-imidazol-4-one, has been synthesized by the reaction of (2E)-1-(4-bromophenyl)-3-{5-bromo-2-[(prop-2-en-1-yl)oxy]benzyl}prop-2-en-1-one with guanidine in the presence of hydrogen peroxide. The product structure was determined by NMR spectroscopy and X-ray analysis. A probable reaction mechanism has been proposed.

Russian Journal of Organic ChemistryVol. 60(12)
Peoples' Friendship University of Russia (RU), Baku State University (AZ), N.D. Zelinsky Institute of Organic Chemistry (RU)
Openalex Percentile: Top 81%
Synthesis and biological activity
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Reaction of Substituted Chalcone with Guanidine in the Presence of Hydrogen Peroxide — Victor N. Khrustalev, I. G. Mamedov · Russian Journal of Organic Chemistry (2024) | TGRS Research Map | TGRS