Modern approaches to diagnosing the course of the wound process in parturient women with obstetric surgical wound infection

Aim - to determine the possibility of using the method of polarization microscopy in diagnosing the course of the wound process in women in labor with infection of the obstetric surgical wound. Materials and methods. 115 women in labor with purulent wounds were examined and treated. The course of the wound process was determined by the method of polarization microscopy by studying the structure of biological media (blood, wound exudate) and the substrate - biopsy from the wound in the solid phase, which were taken before, during treatment, and after it for 2-3 days. To determine the method of polarization microscopy as a diagnostic criterion for the course of the wound process, the results were obtained and compared with the results of clinical, bacteriological, immunological, histological and cytological research methods. Statistical data processing was carried out using the application program package "Microsoft Excel 5.0" and the standard version of "Statistica 8.0". The difference in indicators was recognized as statistically significant at p<0.05. Results. Using the method of polarization microscopy, together with clinical, bacteriological, immunological, histological and cytological research methods, pathogenetic changes in the body of women with purulent wounds in parturient women were explained, clinical manifestations of wound infection were characterized, the course of the wound process was assessed, and the restoration of tissue in the wound to its original functional state was shown. Conclusions. The method of polarization microscopy can be used in clinical practice as an objective criterion of the course of the wound process and the effectiveness of treatment for infected surgical wounds in obstetric practice. The study was performed in accordance with the principles of the Declaration of Helsinki. The study protocol was approved by the Local Ethics Committee of the institution specified in the work. Informed consent of the patients was obtained for the research. The authors declare that there is no conflict of interest.