Berberine Alleviates Kainic Acid‐Induced Acute Epileptic Seizures in Mice via Reshaping Gut Microbiota‐Associated Lipid Metabolism
These findings suggest that BBR exerts neuroprotection against KA-induced epileptic seizures through remodeling gut microbiota-associated lipid metabolism in the colon and hippocampus. BBR may serve as a valuable candidate drug for curing patients with epilepsy.
Authors
- Zuiming Jiang
- Wenting Dai (ORCID: https://orcid.org/0000-0003-0768-7485)
- Xiao‐Yuan Mao (ORCID: https://orcid.org/0000-0002-5149-1204)
- Yong‐Guan Zhu (ORCID: https://orcid.org/0000-0003-3861-8482)
- Yi Xiang
- Zhaoqian Liu (ORCID: https://orcid.org/0000-0001-5724-1516)
Institutions
- Central South University (CN)
- Zhuzhou Central Hospital (CN)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1111/cns.70253
- Citations
- 6
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 4.84
Funders
- National Natural Science Foundation of China