Effectiveness and safety of the XEN45 gel stent compared to trabeculectomy in primary open-angle glaucoma: the Gold-Standard Pathway Study
Similar proportions of eyes with POAG achieved the primary endpoint post-gel stent and post-trabeculectomy. The mean IOP reduction was statistically greater post-trabeculectomy. The gel stent resulted in fewer postoperative interventions, faster/better visual recovery, favourable patient-reported outcomes and fewer specific adverse events, although more SSIs and IOP elevations were observed.
Authors
- E. Randy Craven (ORCID: https://orcid.org/0000-0002-2077-659X)
- Ingeborg Stalmans (ORCID: https://orcid.org/0000-0001-7507-4512)
- Herbert A. Reitsamer (ORCID: https://orcid.org/0000-0002-3607-9430)
- Vanessa Vera
- Iqbal Ike K. Ahmed (ORCID: https://orcid.org/0000-0001-5600-7242)
- Kaweh Mansouri (ORCID: https://orcid.org/0009-0007-3068-3737)
- Antonio Maria Fea (ORCID: https://orcid.org/0000-0002-6551-6054)
- Xuemin Gu
Institutions
- University of Denver (US)
- University of Toronto (CA)
- University of Utah (US)
- Paracelsus Medical University (AT)
- Universitair Ziekenhuis Leuven (BE)
- AbbVie (United States) (US)
- Prism Eye Institute (CA)
- Allergan (United States) (US)
- University of Turin (IT)
- University of Colorado Denver (US)
- KU Leuven (BE)
Publication Details
- Journal
- BMJ Open Ophthalmology
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1136/bmjophth-2024-001696
- Citations
- 3
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 5.12
Funders
- University of Pittsburgh
- Allergan
- University of Colorado School of Medicine, Anschutz Medical Campus