Preoperative liquid biopsy transcriptomic panel for risk assessment of lymph node metastasis in T1 gastric cancer
We developed and validated a novel liquid biopsy-based RSA model that accurately predicts LNM in T1 GC patients. This non-invasive approach could significantly reduce unnecessary surgical interventions and optimize treatment strategies for high-risk T1 GC patients.
Authors
- Tongkun Li (ORCID: https://orcid.org/0009-0009-2625-7641)
- Ping’an Ding (ORCID: https://orcid.org/0000-0002-8163-0711)
- Jiaxiang Wu (ORCID: https://orcid.org/0000-0001-9132-5625)
- Limian Er (ORCID: https://orcid.org/0000-0001-7709-316X)
- Qun Zhao (ORCID: https://orcid.org/0000-0003-1603-3002)
- Jiaxuan Yang (ORCID: https://orcid.org/0009-0003-8985-7720)
- Haotian Wu (ORCID: https://orcid.org/0000-0002-6271-0249)
- Lingjiao Meng (ORCID: https://orcid.org/0000-0001-9316-8774)
- Wenqian Ma (ORCID: https://orcid.org/0009-0003-9099-4888)
- Peigang Yang
- Renjun Gu (ORCID: https://orcid.org/0000-0002-3334-9124)
- Yuan Tian (ORCID: https://orcid.org/0000-0003-2229-5201)
- Ning Meng (ORCID: https://orcid.org/0000-0002-0481-9916)
- Lilong Zhang (ORCID: https://orcid.org/0000-0002-3360-1158)
- Honghai Guo
- Xiaolong Li (ORCID: https://orcid.org/0009-0006-9431-8336)
- Zhenjiang Guo
Institutions
- Hebei Medical University (CN)
- Nanjing University of Chinese Medicine (CN)
- Hengshui University (CN)
- Nanjing General Hospital of Nanjing Military Command (CN)
- Wuhan University (CN)
- Third Hospital of Hebei Medical University (CN)
- Center for Agricultural Resources Research (CN)
- Fourth Hospital of Hebei Medical University (CN)
- First Hospital of Shijiazhuang (CN)
- Renmin Hospital of Wuhan University (CN)
- Baoding People's Hospital (CN)
- Nanjing University (CN)
Publication Details
- Journal
- Journal of Experimental & Clinical Cancer Research
- Published
- 2025-02-07
- DOI
- https://doi.org/10.1186/s13046-025-03305-x
- Citations
- 5
- Primary Topic
- Gastric Cancer Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 7.59