Diagnostic Accuracy of the LiverRisk Score to Detect Increased Liver Stiffness Among a United States General Population and Subgroups
The LRS score is a promising new tool to predict liver fibrosis; however, its diagnostic accuracy attenuates especially among patients aged 18-40 or 60-80 years. The overall sensitivity was only 47.3% at the lowest LRS cut-off. Further studies assessing cost-benefit ratios according to the LRS compared to FIB-4 and other risk scores such as MAF-5 and SAFE are required to determine its usefulness in referral strategies.
Authors
- Laurens A. van Kleef (ORCID: https://orcid.org/0000-0002-2333-1182)
- Harry L.A. Janssen (ORCID: https://orcid.org/0000-0003-2398-8392)
- Willem Pieter Brouwer (ORCID: https://orcid.org/0000-0001-8713-1481)
- Jesse Pustjens
Institutions
- University Health Network (CA)
- Toronto General Hospital (CA)
- Erasmus MC (NL)
Publication Details
- Journal
- Journal of Clinical and Experimental Hepatology
- Published
- 2025-02-06
- DOI
- https://doi.org/10.1016/j.jceh.2025.102512
- Citations
- 5
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 6.77
Funders
- Stichting voor Lever- en Maag-Darm Onderzoek