Exploring physiological beta-hydroxybutyrate level in children treated with the classical ketogenic diet for drug-resistant epilepsy
BHB levels increased rapidly following fasting, reaching the peak at day 2, stabilizing from the end of the first week through three months. The lower reference limit for BHB to ensure KD efficacy should be set at 1.1 mmol/L.
Authors
- Sufang Lin (ORCID: https://orcid.org/0000-0001-5728-1462)
- Zhenliang Ye (ORCID: https://orcid.org/0009-0003-4271-9937)
- Dezhi Cao (ORCID: https://orcid.org/0000-0002-7424-8063)
- Dongfang Zou (ORCID: https://orcid.org/0000-0001-6726-8704)
- Jialun Wen (ORCID: https://orcid.org/0000-0002-1399-5890)
- Ingrid Eileen Scheffer (ORCID: https://orcid.org/0000-0002-2311-2174)
- Jianxiang Liao (ORCID: https://orcid.org/0000-0001-9769-3365)
- Huafang Zou (ORCID: https://orcid.org/0000-0003-3252-4995)
- Patrick Kwan (ORCID: https://orcid.org/0000-0001-7310-276X)
- Man Zhang (ORCID: https://orcid.org/0000-0003-0202-4172)
- Li Chen (ORCID: https://orcid.org/0000-0001-7670-8062)
- Zhibin Chen (ORCID: https://orcid.org/0000-0002-2354-6589)
- Jiong Qin (ORCID: https://orcid.org/0000-0002-9109-3286)
- Xiaoying Qiao
Institutions
- The Royal Melbourne Hospital (AU)
- Royal Children's Hospital (AU)
- The University of Melbourne (AU)
- Peking University (CN)
- Austin Hospital (AU)
- The Alfred Hospital (AU)
- Monash Alfred Psychiatry Research centre (AU)
- Peking University People's Hospital (CN)
- Peking University First Hospital (CN)
- Murdoch Children's Research Institute (AU)
- Shenzhen Children's Hospital (CN)
- Monash University (AU)
Publication Details
- Journal
- Acta Epileptologica
- Published
- 2025-02-07
- DOI
- https://doi.org/10.1186/s42494-024-00199-8
- Citations
- 4
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 4.66
Funders
- Shenzhen Government
- Sanming Project of Medicine in Shenzhen