The Impact of Atorvastatin on Intraprostatic Biomarkers – Prognostic Value of 3LS-score – Follow-up of ESTO1-Trial
Higher atorvastatin lactone concentrations in the prostate tissue were linked to improved pathological variables. Pre-surgery statin intervention reduced MACE risk but no impact on other clinical outcomes was observed. The 3LS from prostate tissue does not seem to be prognostic marker in localized Pca.
Authors
- Aino Siltari (ORCID: https://orcid.org/0000-0002-7814-427X)
- Teemu T. Tolonen (ORCID: https://orcid.org/0000-0003-2029-6497)
- Heimo Syvälä
- T.L.J. Tammela
- Seppo Auriola (ORCID: https://orcid.org/0000-0002-4580-1034)
- Maiju Vertanen
- Eemil Lehtonen
- Teemu Murtola
Institutions
- Tampere University of Applied Sciences (FI)
- Tampere University (FI)
- University of Eastern Finland (FI)
- Tampere University Hospital (FI)
- Tampere University (FI)
- Fimlab (Finland) (FI)
Publication Details
- Journal
- Neoplasia
- Published
- 2025-02-06
- DOI
- https://doi.org/10.1016/j.neo.2025.101132
- Citations
- 2
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- Academy of Finland
- Syöpäsäätiö