Identification and prioritization of novel therapeutic candidates against glutamate racemase from Klebsiella pneumoniae
The investigation of MurI via computational approach and the subsequent analysis of potential inhibitors can pave the way for developing new therapeutic strategies to combat the infections and antibiotic resistance of Klebsiella pneumoniae. This study could significantly help the medical fraternity in the treatment of infections caused by this multidrug-resistant pathogen.
Authors
- Anas Shamsi (ORCID: https://orcid.org/0000-0001-7055-7056)
- Farah Anjum (ORCID: https://orcid.org/0000-0002-8597-6015)
- Ankit Kumar (ORCID: https://orcid.org/0000-0002-2059-5545)
- Md. Imtaiyaz Hassan (ORCID: https://orcid.org/0000-0002-3663-4940)
- Rashmi Prabha Singh (ORCID: https://orcid.org/0000-0003-4475-3007)
Institutions
- Taif University (SA)
- Ajman University (AE)
- Jamia Millia Islamia (IN)
- Sharda University (IN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-02-06
- DOI
- https://doi.org/10.1371/journal.pone.0317622
- Citations
- 2
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 3.01
Funders
- Taif University