The association of triglyceride-glucose and triglyceride-glucose related indices with the risk of heart disease in a national cohort study

In the national population study, higher TyG-BMI, TyG-WC, and TyG-WHtR indices were significantly associated with an increased risk of heart disease, with TyG-BMI and TyG-WC showing stronger correlations. While this association was evident in non-T2D patients, only TyG-BMI was associated with heart disease incidence in T2D patients, underscoring the necessity for further investigation.

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Publication Details

Journal
Cardiovascular Diabetology
Published
2025-02-06
DOI
https://doi.org/10.1186/s12933-025-02621-y
Citations
15
Primary Topic
Diabetes, Cardiovascular Risks, and Lipoproteins
Type
article
Field-Weighted Citation Impact
19.42

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article

The association of triglyceride-glucose and triglyceride-glucose related indices with the risk of heart disease in a national cohort study

Kexin Zhang, Rong He, Xiaodi Tang
15 citations
Cardiovascular Diabetology
Diabetes, Cardiovascular Risks, and Lipoproteins
19.42
article

The association of triglyceride-glucose and triglyceride-glucose related indices with the risk of heart disease in a national cohort study

Kexin Zhang, Rong He, Xiaodi Tang
article en
15 citations

Abstract

In the national population study, higher TyG-BMI, TyG-WC, and TyG-WHtR indices were significantly associated with an increased risk of heart disease, with TyG-BMI and TyG-WC showing stronger correlations. While this association was evident in non-T2D patients, only TyG-BMI was associated with heart disease incidence in T2D patients, underscoring the necessity for further investigation.

Cardiovascular DiabetologyVol. 24(1)
Beijing Tsinghua Chang Gung Hospital (CN), Tsinghua University (CN)
Guangzhou Medical University, Peking Union Medical College Hospital, Peking Union Medical College, Chinese People’s Liberation Army
Good health and well-being
Openalex Percentile: Top 1%
Diabetes, Cardiovascular Risks, and Lipoproteins
19.42
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