Increased nuclear expression of DNA damage inducible transcript 4 can serve as a potential prognostic biomarker in patients with gliomas: a study based on data mining and experimental tools
Our findings suggest that nuclear DDIT4 expression may serve as a potential prognostic biomarker and therapeutic target in glioma patients. However, further studies with larger sample sizes and long-term follow-ups are needed to validate these observations and confirm their clinical relevance.
Authors
- Zahra Madjd (ORCID: https://orcid.org/0000-0001-7329-2583)
- Fatemeh Tajik (ORCID: https://orcid.org/0000-0001-9764-2947)
- Fahimeh Fattahi (ORCID: https://orcid.org/0000-0002-2563-0004)
- Alireza Sadeghipour (ORCID: https://orcid.org/0000-0002-4590-1318)
- Leili Saeednejad Zanjani (ORCID: https://orcid.org/0000-0002-5035-3766)
- Farnoosh Sedaghati
Institutions
- Arak University of Medical Sciences (IR)
- Iran University of Medical Sciences (IR)
- Aja University of Medical Sciences (IR)
- Rasool Akram Hospital (IR)
- University of California, Irvine Medical Center (US)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-02-06
- DOI
- https://doi.org/10.1007/s12672-025-01865-0
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00