An Easy and Quick Risk-Stratified Early Forewarning Model for Septic Shock in the Intensive Care Unit: Development, Validation, and Interpretation Study
The SORP demonstrated accurate forewarning and a reliable risk stratification capability. Among patients forewarned as high risk, similar pathophysiological phenotypes and high mortality were observed in both those subsequently diagnosed as having SS and those without such a diagnosis. NS_HR patients, overlooked by the Sepsis-3 definition, may provide further insights into the pathophysiological processes of SS onset and help to complement its diagnosis and precise management. The importance of precise fluid resuscitation management in SS patients with renal dysfunction is further highlighted. For convenience, an online service for the SORP has been provided.
Authors
- Xiaopei Shen (ORCID: https://orcid.org/0000-0002-0004-4228)
- Zimei Zhang (ORCID: https://orcid.org/0000-0003-3428-9482)
- Haidan Yan (ORCID: https://orcid.org/0000-0003-0214-7471)
- Riping Wu
- Guanghao Liu (ORCID: https://orcid.org/0000-0001-8386-5410)
- Shixiang Zheng (ORCID: https://orcid.org/0000-0001-9543-9953)
- Ting Chen (ORCID: https://orcid.org/0000-0002-3228-9166)
- Jun He (ORCID: https://orcid.org/0000-0003-1510-1093)
- Yingying Yu (ORCID: https://orcid.org/0009-0004-7828-8646)
- Huaguo Shao (ORCID: https://orcid.org/0009-0000-7633-6879)
- Hao Fu (ORCID: https://orcid.org/0009-0003-0152-6127)
- Yichang Xu
- Li Han
- Haibo Zhu
Institutions
- Fujian Medical University (CN)
- Union Hospital (CN)
- South China University of Technology (CN)
- Tsinghua University (CN)
Publication Details
- Journal
- Journal of Medical Internet Research
- Published
- 2025-02-06
- DOI
- https://doi.org/10.2196/58779
- Citations
- 5
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 6.77