Early Diagnosis and Monitoring of Adaptive Immune Response in a Cohort of Mild Mpox Patients During the 2022 Wave
Our data highlight the relevance of specific IgA testing early after the symptom onset, suggesting a possible role as a marker in early diagnosis, especially in close contact subjects. Furthermore, the different maturation states of effector cells in HIV+ patients, together with high Treg levels, may lead us to better understand the role of MPXV-HIV co-infection and identify potential cellular markers to monitor the excessive immune activation involved in mpox disease progression.
Authors
- Sara Caldrer (ORCID: https://orcid.org/0000-0002-2379-1082)
- Andrea Matucci (ORCID: https://orcid.org/0000-0001-9368-850X)
- Annalisa Donini
- Concetta Castilletti (ORCID: https://orcid.org/0000-0001-9819-236X)
- Chiara Piubelli (ORCID: https://orcid.org/0000-0002-5739-3795)
- Federico Giovanni Gobbi (ORCID: https://orcid.org/0000-0002-6899-4545)
- Andrea Angheben (ORCID: https://orcid.org/0000-0003-4545-8034)
- Silvia Accordini (ORCID: https://orcid.org/0000-0003-1857-1429)
- Antonio Mori (ORCID: https://orcid.org/0000-0003-2845-5931)
- Cristina Mazzi (ORCID: https://orcid.org/0000-0002-4561-3447)
- Niccolò Ronzoni (ORCID: https://orcid.org/0000-0003-2966-5973)
- Maddalena Cordioli (ORCID: https://orcid.org/0000-0002-4804-2379)
- Natasha Gianesini (ORCID: https://orcid.org/0009-0008-4330-1758)
- Evelina Tacconelli
Institutions
- University of Verona (IT)
- Ospedale Sacro Cuore Don Calabria (IT)
Publication Details
- Journal
- Microorganisms
- Published
- 2025-02-06
- DOI
- https://doi.org/10.3390/microorganisms13020355
- Citations
- 1
- Primary Topic
- Poxvirus research and outbreaks
- Type
- article
- Field-Weighted Citation Impact
- 1.04
Funders
- Ministero della Salute