2-(Heptylthio)pyrimidine-4,6-diamine

Thiopyrimidines represent one of the most active classes of compounds, possessing a wide spectrum of biological activities. Herein, we report the synthesis of 2-(heptylthio)pyrimidine-4,6-diamine (HPDA) via S-alkylation. The structure of HPDA was elucidated using 1H and 13C nuclear magnetic resonance (NMR), heteronuclear multiple bond correlation (HMBC), high resolution mass (HRMS), and infrared (IR) spectroscopies.

Authors

Institutions

Publication Details

Journal
Molbank
Published
2025-02-06
DOI
https://doi.org/10.3390/m1965
Citations
2
Primary Topic
Synthesis and Characterization of Heterocyclic Compounds
Type
article
Field-Weighted Citation Impact
1.87

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

2-(Heptylthio)pyrimidine-4,6-diamine

Tursunali Kholikov, Malokhat Uktamova, Kohei Torikai, Gulrukh Salieva
2 citations
Molbank
Synthesis and Characterization of Heterocyclic Compounds
1.87
article

2-(Heptylthio)pyrimidine-4,6-diamine

Tursunali Kholikov, Malokhat Uktamova, Kohei Torikai, Gulrukh Salieva
article en
2 citations

Abstract

Thiopyrimidines represent one of the most active classes of compounds, possessing a wide spectrum of biological activities. Herein, we report the synthesis of 2-(heptylthio)pyrimidine-4,6-diamine (HPDA) via S-alkylation. The structure of HPDA was elucidated using 1H and 13C nuclear magnetic resonance (NMR), heteronuclear multiple bond correlation (HMBC), high resolution mass (HRMS), and infrared (IR) spectroscopies.

MolbankVol. 2025(1)
Kyushu University (JP), National University of Uzbekistan (UZ)
Japan International Cooperation Agency, Japan Science and Technology Agency, Science and Technology Research Partnership for Sustainable Development
Openalex Percentile: Top 18%
Synthesis and Characterization of Heterocyclic Compounds
1.87
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.