Non-Hodgkin Lymphoma Manifesting as Bilateral Tonsillar Hypertrophy: A Case Report

Non-Hodgkin lymphoma (NHL) is a diverse group of lymphoid malignancies, with varied clinical presentations depending on the anatomical site of involvement. Although typically presenting with nodal disease, extranodal manifestations are not uncommon. NHL involving Waldeyer's ring is considered rare, with the palatine tonsils being the most frequently affected location. This case report presents a 30-year-old male patient with bilateral tonsillar hypertrophy, ultimately diagnosed as NHL. The patient presented with a persistent sore throat, dysphagia, and snoring associated with sleep disturbances. Detailed physical examination, imaging studies, and histopathological analysis of the excised tonsillar tissue confirmed the diagnosis. This case underscores the importance of considering NHL in the differential diagnosis of persistent tonsillar enlargement to ensure timely and appropriate management.

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Publication Details

Journal
Cureus
Published
2025-02-06
DOI
https://doi.org/10.7759/cureus.78628
Citations
1
Primary Topic
Lymphoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
1.47
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article

Non-Hodgkin Lymphoma Manifesting as Bilateral Tonsillar Hypertrophy: A Case Report

Hashim S Almishhadany, Asal A Al Azzawi
1 citations
Cureus
Lymphoma Diagnosis and Treatment
1.47
article

Non-Hodgkin Lymphoma Manifesting as Bilateral Tonsillar Hypertrophy: A Case Report

Hashim S Almishhadany, Asal A Al Azzawi
article en
1 citations

Abstract

Non-Hodgkin lymphoma (NHL) is a diverse group of lymphoid malignancies, with varied clinical presentations depending on the anatomical site of involvement. Although typically presenting with nodal disease, extranodal manifestations are not uncommon. NHL involving Waldeyer's ring is considered rare, with the palatine tonsils being the most frequently affected location. This case report presents a 30-year-old male patient with bilateral tonsillar hypertrophy, ultimately diagnosed as NHL. The patient presented with a persistent sore throat, dysphagia, and snoring associated with sleep disturbances. Detailed physical examination, imaging studies, and histopathological analysis of the excised tonsillar tissue confirmed the diagnosis. This case underscores the importance of considering NHL in the differential diagnosis of persistent tonsillar enlargement to ensure timely and appropriate management.

CureusVol. 17(2)
University of Sharjah (AE)
Zero hunger
Openalex Percentile: Top 23%
Lymphoma Diagnosis and Treatment
1.47
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