A minimally invasive animal model of atherosclerosis and neointimal hyperplasia for translational research
Rabbit models show similar lipid metabolism as humans. Stent-retriever mediated endothelial denudation causes neointimal hyperplasia and lumen narrowing. This minimal invasive model allows for clinical translation, including pharmacological investigations and vessel wall imaging.
Authors
- Bastian Popper (ORCID: https://orcid.org/0000-0003-1517-695X)
- Vanessa F. Schmidt (ORCID: https://orcid.org/0000-0002-7067-2203)
- Anne von Thaden
- Astrid Jeibmann (ORCID: https://orcid.org/0000-0003-3759-3164)
- Osman Öcal (ORCID: https://orcid.org/0000-0001-5234-1921)
- Jens Ricke (ORCID: https://orcid.org/0000-0001-8762-8594)
- Moritz Wildgruber (ORCID: https://orcid.org/0000-0002-7228-6963)
- Max L. A. Ebert
- Melanie A. Kimm (ORCID: https://orcid.org/0000-0001-6833-9738)
- Sandra Elges
- Olaf Dietrich (ORCID: https://orcid.org/0000-0001-6182-5039)
- Max Seidensticker (ORCID: https://orcid.org/0000-0002-2481-5410)
Institutions
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- LMU Klinikum (DE)
- University Hospital Münster (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- European Radiology Experimental
- Published
- 2025-02-06
- DOI
- https://doi.org/10.1186/s41747-025-00558-1
- Citations
- 1
- Primary Topic
- Coronary Interventions and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- Deutsche Forschungsgemeinschaft