<scp>VEGFR3</scp> pathway in corneal transplantation

These findings underscore the importance of understanding the VEGF-C/D-VEGFR3 pathway in modulating immune responses and inflammation in corneal transplantation, particularly in HR cases. Targeting this pathway could offer novel therapeutic avenues to mitigate inflammation and improve graft survival. Further research is warranted to elucidate the underlying mechanisms and validate these findings, potentially enhancing transplant outcomes, especially in HR patients.

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Publication Details

Journal
Acta Ophthalmologica
Published
2025-02-06
DOI
https://doi.org/10.1111/aos.17457
Primary Topic
Corneal Surgery and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

VEGFR3 pathway in corneal transplantation

Antonio Laborante, Chiara De Gregorio, Graziana Esposito, Andrea De Luca et al.
Acta Ophthalmologica
Corneal Surgery and Treatments
article

VEGFR3 pathway in corneal transplantation

Antonio Laborante, Chiara De Gregorio, Graziana Esposito, Andrea De Luca, Alessandra Micera, Marco Coassin, Bijorn Omar Balzamino, Daniele Gaudenzi, Francesco Cutrupi, Mariateresa Laborante, Antonio Di Zazzo
article en

Abstract

These findings underscore the importance of understanding the VEGF-C/D-VEGFR3 pathway in modulating immune responses and inflammation in corneal transplantation, particularly in HR cases. Targeting this pathway could offer novel therapeutic avenues to mitigate inflammation and improve graft survival. Further research is warranted to elucidate the underlying mechanisms and validate these findings, potentially enhancing transplant outcomes, especially in HR patients.

Acta OphthalmologicaVol. 103(4)
Università Campus Bio-Medico (IT), Casa Sollievo della Sofferenza (IT), Fondazione G.B. Bietti (IT), Campus Bio Medico University Hospital (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Good health and well-being
Openalex Percentile: Top 97%
Corneal Surgery and Treatments
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<scp>VEGFR3</scp> pathway in corneal transplantation — Antonio Laborante, Chiara De Gregorio, et al. · Acta Ophthalmologica (2025) | TGRS Research Map | TGRS