CENP-A/CENP-B uncoupling in the evolutionary reshuffling of centromeres in equids

We propose that the uncoupling between CENP-B and CENP-A may have played a role in the extensive evolutionary reshuffling of equid centromeres. This study provides new insights into the complexity of centromere organization in a largely biodiverse world where the majority of mammalian species still have to be studied.

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Publication Details

Journal
Genome biology
Published
2025-02-06
DOI
https://doi.org/10.1186/s13059-025-03490-0
Citations
8
Primary Topic
Chromosomal and Genetic Variations
Type
article
Field-Weighted Citation Impact
14.00

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article

CENP-A/CENP-B uncoupling in the evolutionary reshuffling of centromeres in equids

Elena Raimondi, Solomon G. Nergadze, Elena Giulotto, Eleonora Cappelletti et al.
8 citations
Genome biology
Chromosomal and Genetic Variations
14.00
article

CENP-A/CENP-B uncoupling in the evolutionary reshuffling of centromeres in equids

Elena Raimondi, Solomon G. Nergadze, Elena Giulotto, Eleonora Cappelletti, Francesca M. Piras, Marialaura Biundo
article en
8 citations

Abstract

We propose that the uncoupling between CENP-B and CENP-A may have played a role in the extensive evolutionary reshuffling of equid centromeres. This study provides new insights into the complexity of centromere organization in a largely biodiverse world where the majority of mammalian species still have to be studied.

Genome biologyVol. 26(1)
University of Pavia (IT), Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani (IT), University Hospital Foundation (CA), Istituti di Ricovero e Cura a Carattere Scientifico (IT)
U.S. Department of Agriculture, Università degli Studi di Milano, Dipartimenti di Eccellenza, University of Galway, Deutsche Forschungsgemeinschaft, Bundesministerium für Bildung und Forschung, Ministero dell’Istruzione, dell’Università e della Ricerca, Università degli Studi di Pavia, German Network for Bioinformatics Infrastructure, National Institute of Food and Agriculture
Zero hunger
Openalex Percentile: Top 1%
Chromosomal and Genetic Variations
14.00
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