Renal Tubular Epithelial Cell-Derived IL-7 Drives Expansion and Protective Effects of Double-Negative T Cells in Acute Kidney Injury
These results establish IL-7 as pivotal for DN T cell expansion and highlight RTECs' role in DN T cell homeostasis.
Authors
- Mohanraj Sadasivam (ORCID: https://orcid.org/0000-0002-3132-2948)
- Sepideh Gharaie
- Hamid Rabb (ORCID: https://orcid.org/0000-0002-4761-1103)
- Abdel Rahim A. Hamad (ORCID: https://orcid.org/0000-0003-3148-4020)
- Sanjeev Noel (ORCID: https://orcid.org/0000-0001-9818-1177)
- Kyungho Lee (ORCID: https://orcid.org/0000-0003-2627-0220)
Institutions
- University of Iowa (US)
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
Publication Details
- Journal
- Immunological Investigations
- Published
- 2025-02-06
- DOI
- https://doi.org/10.1080/08820139.2025.2462537
- Citations
- 1
- Primary Topic
- Immune responses and vaccinations
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- National Research Foundation
- Korea Health Industry Development Institute