Cesium Carbonate-Catalyzed Oxidative <i>Cross</i>-Dehydrogenative Thiolation of Phosphonothioates
Herein, we report an aerobic oxidative <i>cross</i>-dehydrogenative coupling (CDC) reaction between thiols and phosphonothioates. The reactions were conducted under mild and transition-metal-free conditions in the presence of air. Not only aryl thiols but also alkyl thiols were successfully coupled with phosphonothioates to form the corresponding phosphorodithioates in good to excellent yields.
Authors
- Chin‐Fa Lee (ORCID: https://orcid.org/0000-0003-0735-5691)
- Rekha Bai (ORCID: https://orcid.org/0000-0001-9080-0754)
- Indrajit Karmakar (ORCID: https://orcid.org/0000-0002-2713-8080)
- Sung‐Hung Lee
- Hsiu‐Te Hung
Institutions
- National Chung Hsing University (TW)
- National Taipei University (TW)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2025-02-06
- DOI
- https://doi.org/10.1021/acs.joc.4c02718
- Citations
- 8
- Primary Topic
- Sulfur-Based Synthesis Techniques
- Type
- article
- Field-Weighted Citation Impact
- 7.49
Funders
- National Chung-Hsing University
- National Science and Technology Council