Hepatic and renal functions of paediatric patients with thalassaemia: a cross-sectional study from two large thalassaemia centres in Sri Lanka

Elevation of hepatic transaminases is common among children with thalassaemia, especially among the subset of patients with haemoglobin E β-thalassaemia and those with high ferritin. Milder reductions in eGFR are noted in some patients with transfusion-dependent β-thalassaemia major.

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Journal
BMJ Open
Published
2025-02-01
DOI
https://doi.org/10.1136/bmjopen-2024-089784
Primary Topic
Hemoglobinopathies and Related Disorders
Type
article
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article

Hepatic and renal functions of paediatric patients with thalassaemia: a cross-sectional study from two large thalassaemia centres in Sri Lanka

Sachith Mettananda, Hashan Pathiraja, Meranthi Fernando, Raveen Thennakoon et al.
BMJ Open
Hemoglobinopathies and Related Disorders
article

Hepatic and renal functions of paediatric patients with thalassaemia: a cross-sectional study from two large thalassaemia centres in Sri Lanka

Sachith Mettananda, Hashan Pathiraja, Meranthi Fernando, Raveen Thennakoon, Anuja Premawardhena, Roshitha De Silva, Wasana Wijenayake, D. C. Bandara
article en

Abstract

Elevation of hepatic transaminases is common among children with thalassaemia, especially among the subset of patients with haemoglobin E β-thalassaemia and those with high ferritin. Milder reductions in eGFR are noted in some patients with transfusion-dependent β-thalassaemia major.

BMJ OpenVol. 15(2)
University of Kelaniya (LK), Vavuniya General Hospital (LK), Colombo North Teaching Hospital (LK)
Good health and well-being
Openalex Percentile: Top 97%
Hemoglobinopathies and Related Disorders
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