<scp>LncRNA</scp>‐<scp>MEG3</scp> Mediated Diabetic Cerebral Ischemia–Reperfusion Injury‐Induced Apoptosis via Modulating Interaction Between Annexin <scp>A2</scp> and Akt in Mitochondria
The outcomes provided clinical evidence that lncRNA-MEG3 appeared as an unfavorable prognostic factor for diabetic CIRI and revealed that lncRNA-MEG3 knockdown could be protective against diabetic CIRI-induced mitochondria-related apoptosis through modulating Anxa2 binding to Akt in mitochondria.
Authors
- Wang Zh (ORCID: https://orcid.org/0000-0002-1800-2384)
- Zhi Ye (ORCID: https://orcid.org/0000-0002-7678-0926)
- Cheng Chen (ORCID: https://orcid.org/0000-0003-1053-3217)
- Wanqing Zhou (ORCID: https://orcid.org/0000-0003-2214-8500)
- Bei Sun (ORCID: https://orcid.org/0000-0001-6688-2294)
- Yongqiu Xie
- Yanfei Zhao
- Pingping Xia
- Di Xiong (ORCID: https://orcid.org/0009-0009-6445-7863)
- Chongyi Tan
Institutions
- Central South University (CN)
- Hainan General Hospital (CN)
- Zhuzhou Central Hospital (CN)
- Xiangya Hospital Central South University (CN)
- Hainan Medical University (CN)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1111/cns.70242
- Citations
- 5
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 4.68
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hunan Province