Metatranscriptomes-based sequence similarity networks uncover genetic signatures within parasitic freshwater microbial eukaryotes
Although no universal marker for parasitism was identified, candidate genes can be proposed at a fine taxonomic scale. We notably provide several protein families that could serve as keys to understanding host-parasite interactions representing pathogenicity factors (e.g., involved in hijacking host resources, or associated with immune evasion mechanisms). All these protein families could offer valuable insights for developing antiparasitic treatments in health and economic contexts. Video Abstract.
Authors
- Arthur Monjot (ORCID: https://orcid.org/0000-0002-6978-4785)
- Cécile Lepère (ORCID: https://orcid.org/0000-0003-4767-0477)
- Lucie Bittner (ORCID: https://orcid.org/0000-0001-8291-7063)
- J. Rousseau
Institutions
- Centre National de la Recherche Scientifique (FR)
- École Pratique des Hautes Études (FR)
- Institut Universitaire de France (FR)
- Université Clermont Auvergne (FR)
- Sorbonne Université (FR)
- Institut de Systématique, Évolution, Biodiversité (FR)
- Laboratoire Microorganismes Génome et Environnement (FR)
- Clermont Université (FR)
Publication Details
- Journal
- Microbiome
- Published
- 2025-02-06
- DOI
- https://doi.org/10.1186/s40168-024-02027-0
- Citations
- 4
- Primary Topic
- Protist diversity and phylogeny
- Type
- article
- Field-Weighted Citation Impact
- 3.22
Funders
- Agence Nationale de la Recherche
- Institut Universitaire de France
- Université Clermont-Auvergne