MT2A promotes angiogenesis in chronically ischemic brains through a copper–mitochondria regulatory mechanism
MT2A can promote angiogenesis in chronically ischemic brains by neutralizing excessive copper ions and rescuing CPO-induced mitochondrial dysfunction.
Authors
- Chuan Chen (ORCID: https://orcid.org/0009-0000-4316-4388)
- Hui Wang (ORCID: https://orcid.org/0000-0003-1663-684X)
- Baoyu Zhang (ORCID: https://orcid.org/0000-0001-5211-1069)
- Yang Yang (ORCID: https://orcid.org/0000-0003-4981-4745)
- Lei Wei (ORCID: https://orcid.org/0000-0001-5140-0504)
- Cong Ling (ORCID: https://orcid.org/0000-0003-3953-0108)
- Cian Yao
- Chuyang Tai
Institutions
- Sun Yat-sen University (CN)
- Third Affiliated Hospital of Sun Yat-sen University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-02-06
- DOI
- https://doi.org/10.1186/s12967-025-06163-5
- Citations
- 13
- Primary Topic
- Mitochondrial Function and Pathology
- Type
- article
- Field-Weighted Citation Impact
- 10.48