Dose response relation for optic nerve atrophy at low-dose rate brachytherapy of uveal melanoma
Significant dose-response curves were found for optic nerve atrophy at low dose rate brachytherapy. A standard position of COB applicators was identified that allows estimation of the dose-response relation from the scleral dose of the applicator for risk estimation without fundus photographs. This larger data set enhances the knowledge of dose-response relationships for irradiation near the optic nerve.
Authors
- W. Sauerwein (ORCID: https://orcid.org/0000-0002-5027-5913)
- Miltiadis Fiorentzis (ORCID: https://orcid.org/0000-0001-7868-5167)
- Eva Biewald (ORCID: https://orcid.org/0000-0002-5941-1686)
- Maja Guberina (ORCID: https://orcid.org/0000-0003-3218-0539)
- Tobias Kiefer
- Christoph Pöttgen (ORCID: https://orcid.org/0000-0002-9224-9318)
- Nika Guberina
- Sami Dalbah
- Ekaterina Sokolenko (ORCID: https://orcid.org/0000-0001-8675-7001)
- H. G. Manke (ORCID: https://orcid.org/0000-0003-2542-438X)
- Tobias Grunewald (ORCID: https://orcid.org/0000-0003-4909-1129)
- Leyla Jabbarli (ORCID: https://orcid.org/0000-0001-7370-5077)
- Christian Pieter Hoffmann (ORCID: https://orcid.org/0000-0002-5282-6950)
- Martin Stuschke (ORCID: https://orcid.org/0000-0001-6836-0940)
- Dirk Flühs
- Andreas Foerster
- Nikolaos Emmanouel Bechrakis (ORCID: https://orcid.org/0000-0002-0180-1112)
- Philipp Rating (ORCID: https://orcid.org/0000-0003-3621-9007)
- Norbert Bornfeld
Institutions
- TU Dortmund University (DE)
- Essen University Hospital (DE)
- West German Heart and Vascular Center Essen (DE)
- University of Duisburg-Essen (DE)
Publication Details
- Journal
- Radiotherapy and Oncology
- Published
- 2025-02-06
- DOI
- https://doi.org/10.1016/j.radonc.2025.110775
- Citations
- 3
- Primary Topic
- Ocular Oncology and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 5.12